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Airlines suspend Middle East flights after US, Israel strikes on Iran

DUBAI, Feb 28 (Reuters) - Global airlines suspendedflights across the Middle East on Saturday after the United States and Israel launched strikes on Iran, plunging the region into a renewed military confrontation.

Flight maps showed the airspace over Iran virtually empty as Israel said it struck Iran and the U.S. military initiated a series of strikes against targets in the country. Iran retaliated with a salvo of missiles.

An Iranian flag flutters, as Israel and the U.S. launched strikes on Iran, in Tehran, Iran, February 28, 2026. Majid Asgaripour/WANA (West Asia News Agency) via REUTERS

Factbox-Airlines cancel flights after US, Israel strikes on Iran

Feb 28 (Reuters) - Global airlines cancelled flights across the Middle East on Saturday after the United States and Israel launchedstrikes on Iran, plunging the region into a new conflict.

Airspace over Iran and Iraq was empty on Saturday morning, maps by flight-tracking service Flightradar24 showed.

Below is the latest on flights listed by airline in alphabetical order:

AIR FRANCE KLM

Air France cancelledflights to and from Tel Aviv in Israel and Beirut in Lebanon for Saturday.

Smoke in the sky over Jerusalem, after missiles were launched from Iran towards Israel, following Israel and U.S. strikes on Iran, February 28, 2026. REUTERS/Ammar Awad

Global reaction to Israeli, US attacks on Iran

Feb 28 (Reuters) - Israel and the United States launched strikes on Iran on Saturday, plunging the Middle East into a renewed military confrontation as President Donald Trump vowed to destroy Tehran's missilearsenal and prevent it from developing a nuclear weapon.

Below is international reaction to the attacks:

DMITRY MEDVEDEV, DEPUTY CHAIRMAN OF RUSSIA'S SECURITY COUNCIL

Smoke rises following an explosion, after Israel and the U.S. launched strikes on Iran, in Tehran, Iran, February 28, 2026. Majid Asgaripour/WANA (West Asia News Agency) via REUTERS

Fears of Mideast war as US-Iran conflict flares

Countries around the world voiced fears of a Middle East conflagration after the United States and Israel launched strikes on Iran Saturday, and Iran targeted US bases in the region in retaliation.

- Iran Guards vow 'severe' punishment -

Iran's Revolutionary Guards vowed to punish the "murderers" of supreme leader Ali Khamenei, after his death was confirmed by state television.

"The hand of revenge of the Iranian nation for a severe, decisive and regrettable punishment for the murderers of the Imam of the Ummah will not let go of them," the Guards said in a statement.

UN chief Antonio Guterres has called for 'an immediate cessation of hostilities and de-escalation'

In Iran attack, Trump seeks what he foreswore -- regime change

Launching a major attack alongside Israel against Iran, US President Donald Trump is openly pursuing the goal he once adamantly rejected -- regime change.

Trump, who ordered a military buildup in the Middle East unseen since the 2003 invasion of Iraq, made clear in a video address that the goal of the bombing campaign dubbed "Epic Fury" was to topple the cleric-run state that has long been a US nemesis.

US President Donald Trump announced a large-scale attack on Iran by video message posted on his social media site

Lebanon refuses to be drawn into Iran conflict: PM

Lebanese Prime Minister Nawaf Salam said Saturday that his country refused to be dragged into war, after Israel and the United States launched strikes against Iran.

Authorities fear the Iran-backed Lebanese militant group Hezbollah could become involved in the conflict, which saw the US and Israel bomb Iran on Saturday and Tehran respond with missile attacks.

Just before the operation began, Israel announced it was carrying out strikes on Hezbollah infrastructure in south Lebanon.

Israel on Saturday carried out fresh strikes on south Lebanon

Lebanon's prime minister warns against dragging country into 'adventures'

BEIRUT, Feb 28 (Reuters) - Lebanese Prime Minister Nawaf Salam on Saturday said he would not accept anyone dragging "the country into adventures that threaten its security and unity", in an indirect message to the Iran-backed Lebanese armed group Hezbollah.

In a statement released after Israel and the United States launched strikes on Iran, Salam noted the "serious developments" in the region and called on "all Lebanese to act with wisdom and patriotism, placing Lebanon and the Lebanese people’s interests above any other consideration".

Lebanese Prime Minister Nawaf Salam speaks to journalists at the government headquarters in Beirut, Lebanon, December 3, 2025. REUTERS/Mohamed Azakir/File Photo

Iran leader Khamenei killed in massive US and Israeli attack

Ayatollah Ali Khamenei, Iran's supreme leader since 1989 and sworn enemy of the West, was killed in the opening salvo of a massive US and Israeli attack, sparking a new wave of retaliatory missile strikes from Tehran on Sunday.

Iranian state television confirmed Khamenei's death early Sunday, hours after President Donald Trump announced the killing of the 86-year-old cleric he described as "one of the most evil people in History".

Thousands of people turn out at a central square in Tehran to mourn Iran’s supreme leader Ayatollah Ali Khamenei, who was killed in joint US and Israeli strikes

Trump says US carrying out 'major combat operations' in Iran

By Jasper Ward

WASHINGTON, Feb 28 (Reuters) - U.S. President Donald Trump said on Saturday that the United States had begun "major combat operations" in Iran, warning that there may be U.S. casualties.

The strikes, which Trump said were aimed at destroying Iranian missiles and annihilating its navy, follow repeated U.S.-Israeli warnings that they would strike Iran again if it pressed ahead with its nuclear and ballistic missile programs.

"I do not make this statement lightly. The Iranian regime seeks to kill," Trump said in a video shared on Truth Social.

U.S. President Donald Trump visits a Whataburger in Corpus Christi, Texas, U.S., February 27, 2026. REUTERS/Elizabeth Frantz

Trump says US aims to destroy Iran's military, topple government

US President Donald Trump announced a major attack against Iran on Saturday, vowing to "annihilate" the country's navy and missile sites, and urging Iranians to overthrow their government.

In a video address after the United States and Israel started bombing Iran, Trump made clear the goal was destruction of the Islamic republic's military and toppling of the authorities in power since the 1979 revolution.

US President Donald Trump announced a large-scale attack on Iran by video message posted on his social media site