The Israeli military said it hit three Hamas targets in Gaza Friday after new protests along the border sparked clashes in which health officials said 28 Palestinians were wounded.
There have been repeated clashes along the border fence since September 13, with Palestinians protesters throwing stones and petrol bombs at Israeli troops who have responded with tear gas and live bullets.
On September 15, Israel launched its first air strike on Gaza since early July, targeting the territory's Islamist rulers Hamas.
In Friday's strikes, an Israeli drone hit two Hamas positions, while a tank struck a third, the military said.